In a conference call, Pfizer chairman and chief executive officer Jeffrey B. Kindler announced plans to overhaul the company’s business practices, including 10,000 layoffs (including previously announced cuts of 2,200), which will reduce Pfizer’s staff by 10%, and the closing of several research and manufacturing sites. He remarked that Pfizer’s immediate priorities are to “improve performance and position itself for future success, as well as improve shareholder return.&...